What is laryngeal cancer staging based on?

Laryngeal cancer is staged using the AJCC TNM system, which evaluates the Primary Tumor extension (T), Regional Lymph Node involvement (N), and Distant Metastasis presence (M).

What are the anatomical subsites of the larynx?

The larynx is divided into three subsites: the supraglottis (above the vocal cords), the glottis (the vocal cords), and the subglottis (below the vocal cords).

What is the significance of the T4 stage in laryngeal cancer?

T4 indicates advanced disease. T4a represents moderately advanced local disease (invading through thyroid cartilage or trachea), while T4b represents very advanced local disease (invading prevertebral space, mediastinal structures, or carotid encasement).

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Laryngeal Cancer TNM Staging Calculator (AJCC 8th Ed.)

Anatomical Subsite

Primary Tumor (T)

T1: Tumor limited to vocal cord(s) with normal mobility (may involve anterior/posterior commissures).

Regional Lymph Nodes (N)

N0: No regional lymph node metastasis.

Distant Metastasis (M)

M0: No distant metastasis.

AJCC 8th Edition Output

Calculated Stage Group:

Stage I

TNM formula:T1 N0 M0 (glottis)

Clinical Staging Recommendations

Early stage disease. Mainstay of treatment is single-modality therapy: transoral laser microsurgery (TLM), partial laryngectomy, or definitive radiotherapy to preserve voice and avoid tracheostomy.

AJCC staging requires pathology verification. For informational clinical use only.

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ORL / Laryngeal Cancer Specialization

Laryngeal Cancer TNM Staging Calculator (AJCC 8th Ed.)

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